There's plenty of research about Linear Congruential Generators, if you feel like diving in. They have a few weaknesses, but AFAIK none that would help you here.
The state of the RNG has 48 bits, thus only 2^48 of the possible 2^64 different longs can ever be returned by nextLong. According to the docs, they're "uniformly distributed", and we have no further guarantees than that.
Let me reorder your questions a little:
Another question: What can we say about the lower 48 bits of x? Are all possible values covered, just most of them, or almost none of them?
With no further knowledge than "uniformly distributed", let's ask stochastics: You pick 2^48 numbers at random from a pool of 2^48 numbers. How likely is it that x was picked at least once?
p(x is in the sequence) = 1 - (1 - 1/2^48)^(2^48) = ~63%
Every number has a ~63% chance to be picked, so we'd expect 63% of all possible values of the lower 48 bits to appear at least once, and ~37% of the values to never appear.
Gaining deeper insight into the structure of the RNG (either mathematically or by brute forcing) would yield a more accurate answer, because a LCG is not perfectly uniformly distributed. But it's extremely unlikely for every value to be picked exactly once.
Suppose I pick an arbitrary starting seed m, then call setSeed and call nextLong. Call the returned value x. Given the lower 48 bits of x, I want to recover the upper 16 bits of x. Is it possible?
As per your previous question, there may be multiple possibilities for the upper 16 bits.
You can just advance the java RNG 2^48 times and compare all 2^48 possible long values with your lower 48 bits. But that would take a few hundred years, or $100.000 for a cloud provider.
You can reduce that. Your RNG goes through three states for nextLong(), s0 -> s1 -> s2. The upper 32 bits of s1 are the upper 32 bits of your long; the upper 32 bits of s2 are the lower 32 bits of your long.
Thus, you know the middle 16 bits of s1. You can try all 2^32 possible states for s1 with the known middle bits and advance them once, comparing the new state to the known 32 bits of s2. If you find a match, then you have both s1 and s2, so you can derive the full value of x. Again, you may get multiple x, and then you'll have to manually check.
Brute forcing 2^32 advances should be possible in a couple of hours, if you use optimized code. This is one where I'd dedust the old c compiler.
Some motivating background: It's relatively easy to recover the lower 48 bits of a minecraft world's seed. However, the upper 16 bits are more difficult. The full 64 bit seed is generated by the procedure described in this problem. In addition, can we rule out parts of the lower-48-bits-space to make the search easier?
So there's just 2^16 possible worlds that'd match your lower 48 bits, and you could generate those and compare them to your savegame. Not the fastest or easiest solution, but it's another possible approach.